The ANF Federal Office coordinates the activities of the ANF Branches in response to national issues of importance to nurses. ANF Branches respond to issues at a State and Territory level and actively represent the industrial and professional interests of members at the local level. All Branches have a network of job representatives in workplaces where they have members. Job representatives are the vital link between the ANF and its members.

When a nurse joins the ANF, they join the branch in the State or Territory where they work. There is an ANF branch in each State and Territory of Australia.